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In 1900, the staff of New York's Knickerbocker Hospital attempt to innovate patient care in an era when modern medical practice was still in its infancy, amid the pressure of racial segregation, drug addiction and financial instability.

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Piper trades her comfortable life for an orange jumpsuit and finds unexpected conflict and camaraderie amidst an eccentric group of inmates.

Taylor Schilling, Jason Biggs, Laura Prepon, Kate Mulgrew, Danielle Brooks, Pablo Schreiber, Natasha Lyonne, Uzo Aduba, Taryn Manning, Laverne Cox, Yael Stone, Samira Wiley, Dascha Polanco, Matt Mc Gorry, Elizabeth Rodriguez, Selenis Leyva It's a case of life imitating art when popular pulp novelist Richard Castle (Nathan Fillion) helps the NYPD hunt a killer copycatting his stories, then finds a second calling as a crime-solving member of detective Kate Beckett's (Stana Katic) homicide team.

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