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Delayed or less intense orgasms may be a natural process of aging due to decreased genital blood flow and dulled genital sensations.Genito-pelvic pain/penetration disorder includes fear or anxiety, marked tightening or tensing of the abdominal and pelvic muscles, or actual pain associated with attempts toward vaginal penetration that is persistent or recurrent for at least six months. Estrogen is effective for the treatment of dyspareunia associated with genitourinary syndrome of menopause.

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Testosterone, with and without concomitant use of estrogen, is associated with improvements in sexual functioning in naturally and surgically menopausal women, although data on long-term risks and benefits are lacking.Bupropion has been shown to improve the adverse sexual effects associated with antidepressant use; however, data are limited.

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